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KMID : 0377819840040040518
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Diagnosis and Treatment
1984 Volume.4 No. 4 p.518 ~ p.527
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THESTUDY ON EXPERIMENTAL BRAIN HERNIATION
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Abstract
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With posterior fossa lesion lying adjacent to but outside the brain stem, the effects of increased int racrani al pressure can be produced by several ways depending on its size, location and rate of expansion´of the mass, causing direct brain stem compression and up-. ward or downward herniation of the cerebellum out of `the posterior fossa.
Author sacrificed 30 mongrel cats in which one group harbored expanding subdural laminaria and the other group with balloon.
Visualizing structures deep in the brain, cat´s heads were instantaneousely frozen with liquid nitrogen and were sacrified.in the midline longitudinally. The brain herniations were assessed by measuring the distance between parts of various anatomical structures on the brain in mid-sagittal section.
Most frequently a cerebellar lesion caused upward herniation but sometimes transtentorial doward herniation of the upper brain stem was observed by the acute obstructive hydrocephalus with marked symmetrical dilatation of the both lateral ventricles. The regional brain ischemia was more severe in the acute expanding subdural balloon group than in 1 aminaria-group.
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